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在一项基于人口的研究中,在中风后一年对睡眠呼吸暂停的纵向评估
Lynda D Lisabeth1,2, Guanghao Zhang3, Ronald D Chervin4
1Department of Epidemiology (L.D.L., L.B.M.), University of Michigan School of Public Health, Ann Arbor.
Stroke
|July 24, 2023
概括
睡眠障碍呼吸严重程度在中风后的一年保持稳定,墨西哥裔美国人的阻塞性呼吸暂停指数较高. 中枢呼吸暂停指数在非西班牙裔白人中增加,但在中风后的墨西哥裔美国人中没有增加.
科学领域:
- 神经学 神经学
- 睡眠医学 睡眠医学
- 公共卫生 公共卫生
背景情况:
- 脑卒中是导致残疾的主要原因,睡眠呼吸障碍 (SDB) 是一种常见的并发症.
- 了解中风后的SDB变化对于患者管理和结果至关重要.
研究的目的:
- 描述中风后一年SDB严重程度的变化.
- 检查这些变化整体和种族.
主要方法:
- 利用了科普斯克里斯蒂大脑攻击监测项目的数据.
- 便携式睡眠呼吸暂停测试 (ApneaLink Plus) 在414名首次缺血性中风患者的基线和中风后3,6个月和12个月进行.
- 概括估计方程分析了时间和种族对SDB严重性的影响,并调整了混因素.
主要成果:
- 在中风后的一年中,阻塞性呼吸暂停指数显著增加 (P<0.01).
- 与非西班牙裔白人相比,墨西哥裔美国人的呼吸事件指数和阻塞性呼吸暂停指数更高.
- 中枢呼吸暂停指数在非西班牙裔白人中增加,但在墨西哥裔美国人中保持稳定 (种族-时间相互作用,P=0.01).
结论:
- 在中风后的一年内,SDB的严重程度在很大程度上是稳定的.
- 研究结果表明,对中风后的SDB进行早期评估和治疗可能是有必要的.
- 结果挑战了之前关于随着时间的推移而减少SDB严重性的报道.
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