艾滋病毒蛋白酶抑制剂萨基纳维尔通过向受体二分化来抑制类似收费受体4的激活

Kai Yao1, Zheng Wang1, Cheng Peng2

  • 1Department of Vascular Surgery, The Third Xiangya Hospital, Central South University, Changsha, Hunan Province, P. R. China.

概括

艾滋病毒药物萨基纳维尔 (SQV) 抑制了托尔类受体4 (TLR4) 信号传递,影响了MyD88和TRIF通路. 这表明SQV可以调节TLR4介导的炎症.

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