独立于皮肤颜色,对毛细血管补充时间的可靠评估
Raquel P de Souza Bachour1, Eduardo Lopes Dias1, George C Cardoso1
1Department of Physics, FFCLRP, University of São Paulo, São Paulo, Brazil.
Journal of biophotonics
|July 24, 2023
概括
这项研究开发了一种量化方法来测量毛细血管补充时间 (CRT),它可靠地适用于所有肤色. 这有助于在不同人群中改善 perfusion 评估,从而更好地监测患者.
科学领域:
- 生物医学工程 生物医学工程
- 医学诊断 医学诊断 医学诊断
- 生理学 生理学 生理学
背景情况:
- 毛细血管补充时间 (CRT) 是对外周 perfusion 的临床测量,在资源有限的环境中至关重要.
- 目前的CRT测量方法表现出有限的重复性和可重复性,特别是在肤色较深的人群中.
- 需要客观,可靠的CRT评估工具,适用于各种人群.
研究的目的:
- 开发和验证一种定量毛细血管补充时间 (CRT) 测量技术.
- 评估定量CRT方法在各种菲茨帕特里克皮肤光型中的性能和可重复性.
- 建立在临床环境和远程医疗中强大的CRT测量的基础.
主要方法:
- 使用RGB视频摄像头和极化白色LED照明的可控数字压缩 (7kPa).
- 通过计算绿色通道平均像素强度上的指数回归的时间常数来量化CRT.
- 实施了适应算法,以选择最佳回归区域和降低噪声,标记不可靠的读数.
主要成果:
- 定量CRT方法在所有测试的菲茨帕特里克皮肤光型中显示出良好的性能和可重复性.
- 80%的CRT读数在20%的预期值范围内.
- 对CRT测量的重复标准偏差为17%.
结论:
- 开发的定量CRT方法提供了可靠和可重复的测量,克服了传统方法的局限性,特别是对于更深色的肤色.
- 这项技术对准确的患者分组,持续监测和远程医疗应用具有重大潜力.
- 进一步发展可能会导致在不同的临床环境中广泛采用客观CRT评估.
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