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Updated: Jul 22, 2025

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多组分氧化二化反应为选择性修改N端二甲基化后翻译修改

Benjamin Emenike1, Julia Donovan1, Monika Raj1

  • 1Department of Chemistry, Emory University, Atlanta, Georgia 30322, United States.

Journal of the American Chemical Society
|July 24, 2023
PubMed
概括

我们开发了一种新方法,氧化二化 (OxNiTha),以检测α-N-终端二甲基化 (Nme2) 后翻译修饰. 这种技术选择性地修改蛋白质和中的Nme2位点,使其能够从细胞溶解物中丰富.

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