在一般实践中急性鼻炎后的住院和严重并发症:基于登记册的队列研究
Marius Skow1,2, Guro H Fossum1,3, Sigurd Høye1
1The Antibiotic Centre for Primary Care, Department of General Practice, Institute of Health and Society, University of Oslo, Oslo, Norway.
The Journal of antimicrobial chemotherapy
|July 24, 2023
概括
从急性鼻炎的严重并发症是罕见的. 抗生素处方并没有减少严重的结局,但与住院病例的增加有关,这表明减少处方可能是有益的,特别是对于低风险患者.
科学领域:
- 一般的做法一般的做法
- 传染病流行病学 传染病流行病学
- 抗生素管理局 抗生素管理局
背景情况:
- 急性鼻炎是一种常见的疾病,在全科医院得到治疗.
- 了解并发症率和抗生素处方的影响对于优化患者护理和抗菌药物管理至关重要.
研究的目的:
- 在全科医院调查急性鼻炎的并发症率.
- 为了确定抗生素处方是否会影响鼻炎并发症的发生率.
主要方法:
- 一项回顾性队列研究包括了在挪威全科医院 (2012-2019) 诊断出鼻炎的成年患者.
- 在全科医生咨询,抗生素处方和入院之间进行了数据链接.
- 后勤回归分析了抗生素使用,风险因素和住院和严重并发症等结果之间的关联.
主要成果:
- 确定了超过711,000次鼻炎发作;在研究期间,发作和抗生素处方率都下降了.
- 住院和严重并发症的发生率保持稳定.
- 抗生素处方与住院住院风险较高有关 (aOR 1.8),但并没有严重的并发症.
结论:
- 急性鼻炎的严重并发症很少发生.
- 一般医生的高抗生素处方率没有显示出对并发症的保护作用.
- 一般建议减少抗生素的处方,对高危人群要谨慎.
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