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Updated: Jul 22, 2025

Bacterial Artificial Chromosomes: A Functional Genomics Tool for the Study of Positive-strand RNA Viruses
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Bacterial Artificial Chromosomes: A Functional Genomics Tool for the Study of Positive-strand RNA Viruses

Published on: December 29, 2015

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用三叶草RNA启动的病毒基因组复制的结构基础

Keerthi Gottipati1,2, Sean C McNeme1, Jerricho Tipo3

  • 1Department of Biochemistry and Molecular Biology, Sealy Center for Structural Biology and Molecular Biophysics, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555, USA.

Nucleic acids research
|July 24, 2023
PubMed
概括

肠道病毒使用5'三叶草RNA结构作为分子开关. 这种结构与宿主多C结合蛋白2 (PCBP2) 和病毒3CDpro相互作用,控制病毒翻译和基因组复制之间的过渡.

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