在酸途径突变体中,代谢重编程和改变细胞外特征增加了MRSA对β-乳酸抗生素的耐药性

Merve S Zeden1, Laura A Gallagher1, Emilio Bueno2

  • 1Microbiology, School of Biological and Chemical Sciences, University of Galway, Galway, Ireland.

PLoS pathogens
|July 24, 2023
PubMed
概括

酸通路 (PPP) 酶Pgl对MRSA抗生素耐药性产生影响. 一个pgl突变通过改变细胞壁组件和表面电荷,增加了抗氧化素耐药性,提供了新的抗菌药物标.

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