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Updated: Jul 22, 2025

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Nsp3-N相互作用对于SARS-CoV-2的适应性和毒性至关重要

Pengfei Li1, Biyun Xue2, Nicholas J Schnicker3

  • 1Department of Microbiology and Immunology, University of Iowa, Iowa City, IA 52242.

Proceedings of the National Academy of Sciences of the United States of America
|July 24, 2023
PubMed
概括

在SARS-CoV-2 nsp3蛋白 (nsp3-S676T) 的突变通过影响翻译减少了病毒复制. 核体蛋白 (N-S194L) 的第二个突变恢复了毒性,揭示了影响COVID-19的nsp3-N相互作用.

关键词:
N 蛋白质 N 蛋白质这就是SARS-CoV-2病毒.这是SARS独特的域名.这就是NSP3SP.

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