患有神经omyelitis optica光谱障碍的患者的营养风险
Rui Huang1, Xinyue Huang1, Yuan Wang2
1Department of Neurology, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, 32 West Second Section of First Ring Road, Chengdu 611731, China.
神经omyelitis光学谱系障碍 (NMOSD) 患者面临营养不良的高风险,严重影响他们的生活质量. 解决营养状况对于改善患者的治疗结果至关重要.
科学领域:
- 神经学 神经学
- 临床营养学 临床营养学
- 自免疫性疾病 自免疫性疾病
背景情况:
- 营养与慢性自身免疫性疾病之间的联系已经确立.
- 神经脊髓炎光学谱障碍 (NMOSD) 患者的营养状况仍未得到充分研究.
- 这项研究调查了NMOSD的营养状况,生活质量和相关因素.
研究的目的:
- 通过微量营养评估 (MNA) 来评估NMOSD患者的营养状况.
- 探索营养状况对NMOSD生活质量的影响.
- 确定与NMOSD患者营养不良相关的因素.
主要方法:
- 招募了70名NMOSD患者和66名健康对照.
- 评估人口统计数据,疾病特征和生活状况 (营养,睡眠,焦虑,抑郁,疲劳,生活质量).
- 使用迷你营养评估 (MNA) 进行营养评估并进行统计分析.
主要成果:
- 与健康对照组相比,NMOSD患者的MNA得分明显较低 (20.4对23.3).
- 大约85%的NMOSD患者有营养不良或营养不良的风险.
- 营养不良与较低的生活质量,女性性别,更长的疾病持续时间,焦虑,抑郁,睡眠障碍和疲劳有关. 睡眠障碍是营养不良的一个独立风险因素.
结论:
- 患有NMOSD的患者患营养不良的风险非常高,这与他们的生活质量密切相关.
- 在NMOSD中营养不良源于联合的生理和心理因素.
- 个性化,多方面的干预措施是必要的,以提高NMOSD患者的预后.
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