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Updated: Jul 22, 2025

A Method to Study de novo Formation of Chromatin Domains
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PRC1凝聚物的分散破坏了多组染色体域和循环

Iain Williamson1, Shelagh Boyle2, Graeme R Grimes2

  • 1MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK Iain.Williamson@ed.ac.uk.

Life science alliance
|July 24, 2023
PubMed
概括

多镇压复合体1 (PRC1) 形成影响3D基因组组织的生物分子凝聚物. 用1,6-hexanediol破坏这些凝聚物可逆地改变了染色质的紧缩和位点聚类,这表明疏水性相互作用驱动了基因组组织.

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