在2018年美国预防服务工作组建议和通过COVID-19大流行后,前列腺特异性抗原查的变化
Zhiyu Qian1, Xi Chen2, Alexander P Cole1
1Division of Urological Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Center for Surgery and Public Health, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
European urology oncology
|July 24, 2023
概括
根据2018年的指导方针,前列腺特异性抗原 (PSA) 查增加,但在COVID-19大流行期间下降. 这些发现凸显了建议和干扰对癌症查率的影响.
科学领域:
- 流行病学和公共卫生.
- 在瘤学瘤学.
- 预防医学 预防医学
背景情况:
- 使用前列腺特异性抗原 (PSA) 测试进行前列腺癌查是一个关键的公共卫生问题.
- 2018年美国预防服务工作组 (USPSTF) 更新的建议影响了查实践.
- 随着COVID-19大流行,包括预防性服务在内的医疗保健服务受到严重干扰.
研究的目的:
- 分析前列腺癌PSA查的趋势.
- 评估2018年USPSTF建议对PSA查率的影响.
- 评估COVID-19疫情对PSA查趋势的影响.
主要方法:
- 利用了国家健康访谈调查数据进行分析.
- 使用差异差异 (DID) 分析来检查PSA查趋势.
- 专注于55-69岁的男性,将他们与69岁以上的男性进行比较,并根据社会人口统计学因素进行调整.
主要成果:
- 与2015年相比,2019年PSA查在55-69岁 (+4.6%) 和69岁以上的男性中增加 (+6.5%).
- 与2019年相比,2021年在55-69岁的男性中观察到PSA查的减少 (-3.1%) 在COVID-19爆发后.
- 调整后的DID分析显示,在USPSTF建议或大流行后,年龄组之间的变化率没有显著差异.
结论:
- 2018年USPSTF指南似乎与55-69岁男性PSA查增加有因果关系.
- 与COVID-19相关的预防护理中断可能已经减缓或逆转了这些查进展.
- 需要进一步监测,以了解流行后的PSA查长期趋势.
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