从Radix Saposhnikoviae中提取多糖的提取,净化,结构特征和生物特性:一篇综述
Zhili Rao1, Hongli Zhou2, Qian Li3
1Department of Pharmacy, Chongqing Hospital of Traditional Chinese Medicine/The Fourth Affiliated Clinical Medical College of Chengdu University of Traditional Chinese Medicine, 400021, PR China; Department of Pharmacology, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, Sichuan, PR China.
Journal of ethnopharmacology
|July 24, 2023
概括
来自Radix Saposhnikoviae (PRSs) 的多糖是具有多种生物活动的关键活性成分. 本综述详细介绍了影响PRS含量,提取和净化的因素,强调了它们的治疗潜力.
科学领域:
- 药理学 药理学是指药理学的学科.
- 自然产品 化学 化学
- 药用植物研究 药用植物研究
背景情况:
- (FangFeng) 是一种传统的中医药,用于驱风,缓解疼痛和去除潮湿.
- 多糖类被确定为R.Saposhnikoviae.中的重要生物活性成分.
- 传统用途包括治疗外部综合征,皮肤,类风湿关节痛和与湿度相关的疾病.
研究的目的:
- 审查影响Radix Saposhnikoviae多糖 (PRS) 含量的因素.
- 总结PRS的提取,分离和净化技术.
- 描述PRSs的生物活动.
主要方法:
- 在主要数据库进行文献搜索,包括CNKI,Web of Science和PubMed.
- 收集和分析关于PRS的研究报告.
- 综合有关PRS影响因素,提取,净化和生物活性的信息.
主要成果:
- PRS含量受到种植方法和收获时间的影响.
- 提取方法包括热水,超声波,微波和酶技术;净化涉及蛋白质去除和脱色.
- PRS表现出显著的免疫调节,抗氧化,抗过敏,抗癌和抗骨质疏松活动.
结论:
- 多糖是Radix Saposhnikoviae的重要生物活性成分,具有广泛的治疗潜力.
- 对PRS的进一步研究可以提高R. Saposhnikoviae的利用率,并导致新的药物开发.
- 了解PRS的特性有助于开发R.Saposhnikoviae衍生的治疗方法.
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