在Sjögren综合征中导致点塞损失的原因
Na Eun Kim1, Hyunmin Ahn2,3, Ikhyun Jun1
1The Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea.
Yonsei medical journal
|July 25, 2023
概括
对于Sjögren综合征的点塞通常会自发丢失,特别是较小的尺寸或流量控制器类型. 插头的特性和插入位置对长期维护有影响.
科学领域:
- 眼科医生 眼科 眼科
- 干眼疾病研究 干眼疾病研究
- 眼睛表面疾病 眼睛表面疾病
背景情况:
- 肖格伦综合征 (SS) 经常导致干眼疾病,需要诸如点塞塞等治疗.
- 点塞用于在眼睛表面保留眼,但它们的长期有效性可能会因损失或移除而受到限制.
研究的目的:
- 评估在患有Sjögren综合征的患者中点塞的长期维护率.
- 确定与这些插头自发丢失或故意移除相关的因素.
主要方法:
- 对163名接受点塞的Sjögren综合征患者的回顾性审查.
- 使用Cox比例危险模型分析插头状态 (维护,损失,移除) 和自发损失的风险因素.
主要成果:
- 平均插头维护时间为7.07个月,自发损失率为58%,删除率为14%.
- 自发损失的危险因素包括先前插入,上眼的位置,更小的插头大小和流量控制器插头类型.
- 眼溢出是故意拔掉插头的最常见原因.
结论:
- 点塞特征 (类型,大小) 和插入部位显著影响Sjögren综合征患者的自发损失.
- 个性化策略对于点塞插入,维护和移除至关重要,以优化患者的治疗结果.
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