在ICU患者中小肠细菌过度生长综合征的高患病率:一项观察性研究
Agathi Karakosta1, Konstantinos Bousvaros2, Athanasios Margaritis3
1Department of Anaesthesia and Postoperative Intensive Care, Faculty of Medicine, University of Ioannina, Ioannina, Greece.
Journal of intensive care medicine
|July 25, 2023
概括
小肠细菌过度生长 (SIBO) 影响36.5%的重症患者,增加了呼吸机相关的肺炎和ICU住院. 早期SIBO诊断和治疗对于更好的患者结果至关重要.
科学领域:
- 关键护理医学 关键护理医学
- 胃肠病学 胃肠病学
- 传染性疾病 传染性疾病
背景情况:
- 小肠细菌过度生长 (SIBO) 在重症患者中没有得到充分的研究.
- SIBO与严重的并发症有关.
- 本研究调查了SIBO在ICU中的流行率和影响.
研究的目的:
- 为了确定SIBO在重症患者中的患病率.
- 评估SIBO对呼吸机相关肺炎 (VAP) 的影响.
- 评估SIBO对ICU停留时间 (LOS) 和死亡率的影响.
主要方法:
- 在混合医疗外科ICU的前性观察研究.
- 52名连续的ICU患者进行了间隔的非侵入性乳糖气呼吸测试 (HBTs).
- 基于3,5和/或7天的HBT结果进行SIBO诊断;初始SIBO病例除外.
主要成果:
- 在研究的ICU人群中,SIBO患病率为36.5%.
- SIBO与增加的VAP发病率 (P < .001) 和延长的ICU LOS (P < .033) 显著相关.
- 所有原因的住院死亡率在SIBO阳性和SIBO阴性组之间没有显著差异.
结论:
- 在ICU患者中SIBO的患病率特别高.
- SIBO与增加的VAP和延长的ICU住院时间有关.
- 早期SIBO诊断和治疗对于重症患者至关重要.
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