根据语言,性别和疾病亚型的系统性硬化症患者中,科手功能尺度上的差异项目运行:一种以硬化皮肤病患者为中心的干预网络 (SPIN) 队列研究
Mingyao Xu1, Daphna Harel1, Marie-Eve Carrier2
1New York University, New York, New York.
Arthritis care & research
|July 25, 2023
概括
科手功能量表 (CHFS) 为系统性硬化症患者提供了不同语言,性别和疾病亚型的可比得分. 这确保了对不同患者群体的可靠手部功能评估.
科学领域:
- 类风湿病学 类风湿病学
- 临床评估工具 临床评估工具
- 心理测量 心理测量 心理测量
背景情况:
- 科手功能尺度 (CHFS) 是一种广泛使用的患者报告的结果测量方法,用于评估系统性硬化症中手的功能.
- 确保人口和临床变量之间的得分可比性对于准确的解释和临床实用性至关重要.
研究的目的:
- 评估CHFS的心理测量特性,特别是其在语言,性别和疾病亚型方面的得分可比性.
- 为了确定差异性项目功能 (DIF) 是否会影响CHFS分数在多样化系统性硬化症队列中的有效性.
主要方法:
- 使用确认因素分析 (CFA) 来评估CHFS的单维性.
- 使用多种指标多种原因 (MIMIC) 模型,根据语言,性别和疾病亚型检测DIF.
- 计算了类内相关系数 (ICC) 和皮尔森相关性,以比较未调整和DIF调整的因子得分.
主要成果:
- 总共有2,155名来自硬化皮肤病患者中心干预网络 (SPIN) 队列的参与者被分析.
- 虽然在语言,性别和疾病亚型方面观察到一些项目具有统计学意义的DIF,但其对因子得分的整体影响是可以忽略不计的.
- 未调整和DIF调整分数之间的一致性和相关性非常高 (ICC = 0.999,r = 0.999).
结论:
- 在系统性硬化症患者中,CHFS显示出优异的得分可比性.
- 该尺度的分数可靠且有效,不论患者的语言,性别或特定疾病亚型.
- CHFS是一种强大的工具,用于评估各种系统性硬化症患者的手部功能.
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