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轴性脊柱关节炎的全球功能与疾病活动和功能比移动性和放射性损伤更强烈相关

David Kiefer¹, Jürgen Braun¹, Uta Kiltz¹

¹Ruhr-Universität Bochum, Bochum, Germany.

Arthritis care & research

|July 25, 2023

概括

患者报告的结果显著影响轴性脊柱关节炎 (axSpA) 的全球功能. 然而,对脊柱运动和结构损伤的客观测量显示,与 axSpA.的患者报告的整体功能之间的相关性有限.

科学领域:

类风湿病学类风湿病学
临床测量临床测量
患者报告的结果

背景情况:

脊椎关节炎评估国际社会健康指数 (ASAS HI) 是一个经过验证的患者报告的全球功能在轴性脊椎关节炎 (axSpA) 的结果.
埃皮尼克斯SPINE (ES) 提供客观的脊柱运动量 (运动范围和动力学).

研究的目的:

为了研究全球功能 (ASAS HI) 和axSpA患者的临床措施之间的关系.
评估与疾病活动,身体功能,脊柱运动性和放射性损伤的相关性.

主要方法:

对103名患有放射性和非放射性 axSpA. 的患者进行横截面研究.
评估了浴室结脊柱炎指数 (BASDAI,BASFI,BASMI),ASAS HI和Epionics SPINE (ES) 的指数,这些指数是衡量标准.
评估了脊柱和关节的放射损伤;计算了肯德尔的相关性.

主要成果:

ASAS HI分数与患者报告的结果 (BASDAI,BASFI,背部疼痛) 有显著的相关性.
在ASAS HI和客观脊柱运动 (ES测量) 或放射性损伤之间没有发现显著的相关性.
浴性椎炎计量指数 (BASMI) 显示与ASAS HI的相关性很弱.

结论:

疾病特异性患者报告的结果显著影响axSpA. axSpA的全球功能.
客观的脊柱运动 (ES) 措施对患者报告的整体功能影响有限.
在这个队列中,整体功能并不高度依赖于轴骨架结构损伤的程度.

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