评估COPD患者住院息护理患者的鼓舞性流量峰值
Joshua Borris1, Heather Cook2, Sulgi Chae3
1Department of Practice, Sciences, and Heath Outcomes Research, School of Pharmacy, University of Maryland, Baltimore, MD 21201, USA.
Pharmacy (Basel, Switzerland)
|July 25, 2023
概括
患有晚期COPD的住院息护理患者可以通过干粉吸入器获得足够的药物输送. 它们的峰值吸入流量 (PIFR) 测量证实它们满足有效药物沉积的最低要求.
科学领域:
- 肺部医学 肺部医学
- 呼吸系统护理 呼吸系统护理
背景情况:
- 干粉吸入器 (DPI) 对于COPD管理至关重要,但需要足够的患者峰值吸入流量 (PIFR) 进行有效的肺沉积.
- 晚期慢性肺炎患者,特别是那些接受息治疗的患者,可能会出现肺功能下降,这引发了人们对他们达到最低PIFR (30L/分钟) 能力的担忧.
研究的目的:
- 为了量化住院缓解护理患者中患有晚期COPD的PIFR.
- 评估这些患者是否符合有效的DPI药物递送所需的最低PIFR.
主要方法:
- 纳入标准:住院患者≥18岁,有息治疗咨询和晚期COPD (GOLD C或D). 排除标准:缺乏决策能力或最近的COVID-19感染.
- 使用In-CheckTM装置测量了三次的峰值吸入流量 (PIFR),使用最高读数进行分析.
- 十八名患者被录取.
主要成果:
- 最高PIFR读数的平均值为72.5L/分钟 (±29L/分钟).
- 后期分析显示99.9%的功率将平均最佳PIFR与30L/分钟的最低要求进行比较.
- 与60L/分钟的最佳PIFR相比,功率为51.4%.
结论:
- 患有晚期慢性慢性肺炎的住院息治疗患者表现出足够的PIFR,以通过DPI实现足够的药物输送.
- 这些发现支持在这个患者群体中使用DPI,确保有效的药物管理.
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