沙特阿拉伯出生缺陷的患病率和模式:对观察性研究的系统审查
Ebtihal Elameen Eltyeb1, Majidah Hussain Asiri Halawi1, Thekra Badr Mohammed Tashari1
1Faculty of Medicine, Jazan University, Jizan 45142, Saudi Arabia.
Pediatric reports
|July 25, 2023
概括
本综述强调了沙特阿拉伯出生缺陷的流行和模式,确定心脏,尿生殖,面和神经系统缺陷是最常见的. 记住了诸如血缘关系和母亲健康等危险因素.
科学领域:
- 医学研究 医学研究
- 公共卫生 公共卫生
- 遗传学 是一个遗传学.
背景情况:
- 出生缺陷构成重大威胁,导致残疾和死亡率.
- 了解它们的流行率和模式对于公共卫生倡议至关重要.
研究的目的:
- 综合审查沙特阿拉伯出生缺陷的流行率和模式.
- 综合该地区关于出生缺陷流行病学的现有数据.
主要方法:
- 对PubMed,Science Direct和沙特数字图书馆 (1989-2022) 的1277个记录进行了系统的文献分析.
- 包括关于沙特阿拉伯出生缺陷患病率和模式的观察性研究.
- 排除评论和非相关文章;使用JBI和GRADE工具评估质量和偏差风险.
主要成果:
- 确定了26个符合条件的出版物,涉及297,668名患者.
- 出生缺陷的患病率差异很大,从每1000个活产婴儿中有8.6个到46.5个.
- 常见的缺陷包括心脏,泌尿器,面和神经系统的异常. 血缘关系,叶酸使用,家族病史和母亲的并发症是相关因素.
结论:
- 这些发现提高了对沙特阿拉伯出生缺陷流行率和模式的理解.
- 建议多中心合作和先进的统计模型用于未来的风险因素研究.
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