睡眠与唾液IL-6度相关的行为图分析在机构住院老年人的老年人中
Vanessa Ibáñez-Del Valle1,2,3, Mayra Alejandra Mafla-España1,2, Josep Silva4
1Department of Nursing, Faculty of Nursing and Podiatry, University of Valencia, c/de Méndez y Pelayo, 19, 46010 Valencia, Spain.
Diseases (Basel, Switzerland)
|July 25, 2023
概括
在老年人中,较低的唾液介质素-6 (IL-6) 水平与较差的睡眠效率和更多的觉醒相关. 痴呆症会影响睡眠模式,但不会影响IL-6水平.
科学领域:
- 老年学是一门学科.
- 睡眠医学 睡眠医学
- 神经科学是一个神经科学.
背景情况:
- 睡眠障碍在住院老年人中很普遍,通常与并发症和多药性有关.
- 互乐金-6 (IL-6) 是一种炎症性细胞因子,与睡眠障碍有关.
研究的目的:
- 为了研究唾液IL-6水平与住院老年人的客观睡眠参数之间的关系.
- 探索痴呆症患者和没有痴呆症患者之间睡眠模式和IL-6水平的差异.
主要方法:
- 客观睡眠分析使用动图学.
- 在61名养老院居民的唾液IL-6测量.
- 认知评估包括痴呆症评估 (阿尔茨海默病).
主要成果:
- 较低的唾液IL-6水平与更差的睡眠效率 (p < 0.05) 和增加的夜间觉醒显著相关.
- 动图显示,痴呆症患者的睡眠模式 (睡眠时间,睡觉时间,起床时间) 发生了变化.
- 睡眠模式和使用精神药物之间没有发现显著的相关性.
- 在患有痴呆症和没有痴呆症的个体之间,唾液IL-6水平没有显著差异.
结论:
- 唾液IL-6水平与住院老年人的睡眠质量有关.
- 痴呆症会影响这个人群的客观睡眠参数.
- 需要进一步的研究,以了解和改善住院老年人的睡眠.
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