在不同孕期怀孕期间评估甲状腺功能障碍
Sunita Prajapati1, Gayatri Prajapati2, Vikram Shrestha3
1Patan Hospital, Patan Academy of Health science, Lalitpur, Nepal.
Journal of Nepal Health Research Council
|July 25, 2023
概括
甲状腺功能障碍,特别是甲状腺功能低下症,在孕妇中很常见. 早期诊断和管理对于预防妊娠并发症和确保胎儿健康至关重要.
科学领域:
- 产科和妇科 产科和妇科
- 内分泌学 在内分泌学.
- 生殖健康 生殖健康
背景情况:
- 怀孕期间甲状腺功能障碍与流产,子宫前和胎儿发育受损等不良结果有关.
- 评估妊娠三季度甲状腺疾病的患病率对于及时干预至关重要.
研究的目的:
- 为了确定怀孕妇女甲状腺功能障碍的患病率.
- 为了分析甲状腺疾病在整个怀孕的三个季度的分布.
主要方法:
- 分析了124名孕妇的血清样本.
- 包括自由甲状腺素 (fT4),自由三甲状腺素 (fT3) 和甲状腺刺激激素 (TSH) 在内的激素水平使用化学发光试验进行了测量.
主要成果:
- 在79%的参与者中观察到甲状腺功能低下症;甲状腺功能低下症 (亚临床和初级) 影响了18%.
- 甲状腺疾病在第三季度 (38.4%) 最常见,在第一季度 (34.6%) 和第二季度 (27%) 有显著的发生.
- 平均fT3和fT4水平与妊娠前三个月呈现负相关性,而TSH水平显示非显著的正相关性.
结论:
- 甲状腺功能低下症是孕妇参加三级护理中最常见的甲状腺疾病.
- 早期诊断和迅速治疗甲状腺功能障碍可以显著减少相关的妊娠并发症.
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