阿姆洛迪平诱导的牙扩张的患病率和严重程度
Junima Rajkarnikar1, Samarika Dahal2, Samriddhi Vaidya1
1Department of Periodontics, Nepal Medical College Teaching Hospital, Attarkhel, Nepal.
Journal of Nepal Health Research Council
|July 25, 2023
概括
阿姆洛迪平是一种通道阻塞剂,可在37%的患者中引起牙扩大. 药物剂量,持续时间和口腔卫生不良与这种副作用有显著的相关性.
科学领域:
- 牙科 牙科是指牙科的专业.
- 药理学 药理学是指药理学的学科.
背景情况:
- 药物诱导的牙扩大与抗药,免疫抑制剂和通道阻塞剂有关.
- 阿姆洛迪平是一种常规处方的通道阻断剂.
研究的目的:
- 为了评估服用阿姆洛地平的患者的牙扩张的频率和严重程度.
主要方法:
- 尼泊尔医学院牙科医院对250名患者进行了一项描述性的横截面研究.
- 使用Bokenkamp和Bornhorst指数评估的牙扩大,用于安洛迪平治疗≥3个月的患者.
- 还评估了牙指数,斑块指数,药物剂量和持续时间.
主要成果:
- 牙扩张的患病率为37%,1级为18%,3级为2%.
- 阿姆洛迪平单疗法和组合疗法都显示出类似的扩大水平.
- 阿姆洛迪平的剂量和持续时间,以及牙和斑块指数,与扩大显著相关.
结论:
- 医生应告知患者关于阿姆洛迪平的潜在牙副作用.
- 对于服用阿姆洛迪平的患者来说,优先考虑口腔卫生至关重要.
- 在严重的情况下,可能需要药物替代或口服治疗措施.
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