维生素D补充剂对ADHD儿童大脑映射和行为表现的影响:双盲随机对照试验
Hamid Mirhosseini1, Najmeh Maayeshi2, Hadis Hooshmandi2
1Research Center of Addiction and Behavioral Sciences, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Nutritional neuroscience
|July 25, 2023
概括
维生素D3补充剂与神经反治疗相结合,改善了ADHD儿童的EEG模式. 这种双重方法有效地增加了维生素D水平,并使脑电波活动正常化,提供了一个有前途的治疗策略.
科学领域:
- 神经科学是一个神经科学.
- 儿科 儿科 儿科
- 营养科学 营养科学
背景情况:
- 注意缺陷多动性障碍 (ADHD) 是一种常见的神经发育障碍,与改变的EEG模式和低维生素D水平有关.
- 神经反提供了一种非侵入性的方法来解决ADHD中的脑波异常.
- 在被诊断患有多动症的儿童中,经常观察到维生素D缺乏.
研究的目的:
- 为了评估维生素D3补充剂和神经反治疗在ADHD儿童的综合作用.
- 评估干预后25-基维生素D [25(OH) D]水平和电生理学标记的变化.
主要方法:
- 患有ADHD的儿童接受了多会话的神经反治疗.
- 参与者被分配到接受每周维生素D3 (50,000 IU) 或安慰剂2个月的组.
- 使用定量EEG测量干预前后的背景大脑节奏.
主要成果:
- 在治疗组中,维生素D3补充剂显著增加了25(OH) D水平和血清.
- 神经反导致了theta相对功率,theta/beta和theta/alpha功率比率的显著减少.
- 特定EEG参数的改善与ADHD症状得分 (康纳斯得分) 有显著的相关性.
结论:
- 维生素D3补充剂和神经反的联合使用有效地改善了ADHD儿童的维生素D状况.
- 这种综合方法产生了有利的电生理学变化,表明ADHD管理的潜在治疗益处.
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