糖尿病外围神经病变的患病率和危险因素:中国的一项基于人口的横截面研究
Weimin Wang1, Qiuhe Ji2, Xinwu Ran3
1Department of Endocrinology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
Diabetes/metabolism research and reviews
|July 25, 2023
概括
糖尿病外围神经病变 (DPN) 影响了中国超过三分之二的2型糖尿病患者. 老年人,低收入和受教育程度低的人面临更高的DPN患病率,突出显著的公共卫生问题.
科学领域:
- 内分泌学 在内分泌学.
- 神经学 神经学
- 公共卫生 公共卫生
背景情况:
- 糖尿病外围神经病变 (DPN) 是2型糖尿病 (T2DM) 的常见并发症.
- 评估DPN患病率和风险因素对于T2DM患者群体的有效管理和预防策略至关重要.
研究的目的:
- 确定在中国的一大群2型糖尿病患者中糖尿病外围神经病变 (DPN) 的患病率.
- 为了确定与DPN相关的关键风险因素,在这个人群中.
主要方法:
- 这是一项涉及2017年7月至12月中国24个省份14908名T2DM患者的横截面研究.
- 使用多伦多临床评分系统,神经病症症状评分 (NSS) 和神经病症残疾评分来评估DPN及其严重程度.
主要成果:
- DPN的总体患病率为67.6%,轻度,中度和严重的DPN分别影响了47.7%,33.0%和19.3%的受影响患者.
- DPN的患病率在女性中较高,随着年龄和糖尿病持续时间的增加而增加,随着BMI和教育水平的提高而下降.
- 高血压,糖尿病视网膜病变和糖尿病病与DPN有显著的关联,以及高血糖血红蛋白和较低估计的膜过率.
结论:
- 在中国的T2DM患者中,DPN的患病率很高.
- 老年人,低收入和受教育程度低的个人代表了具有较高DPN风险的关键人口群体.
- 这些发现强调了在易受伤害的T2DM患者小组中对DPN进行有针对性的查和干预计划的需要.
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