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Updated: Jul 21, 2025

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在IRAK-4激酶研究中的新兴趋势

Himanshu Yadav1, Raj Kumar Shirumalla2

  • 1SGT College of Pharmacy, SGT University, Budhera, Gurugram, Haryana, 122505, India.

Molecular biology reports
|July 25, 2023
PubMed
概括

向IRAK-4 (互白素-1受体关联激酶4) 对于治疗各种疾病至关重要. 然而,它的支架效应限制了传统的抑制剂,促使开发了针对蛋白解酶的奇默体 (PROTACs),以完全降解IRAK-4.

关键词:
这是一种自身免疫力.伊拉克四号 - 伊拉克四号在 Protac 中,我们可以使用 Protac.脚手架的效果是一个脚手架效果.有针对性的蛋白质降解降解.

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