印度的Covid-19相关粘菌的卫星流行:一个多站点观察性研究
Aanchal Satija1, Tanu Anand1, Aparna Mukherjee1
1Indian Council of Medical Research, New Delhi, India.
Mycopathologia
|July 25, 2023
概括
COVID-19相关性粘菌菌 (CAM) 是一种严重的真菌感染. 更好的血糖控制和COVID-19后4-6周的警可以帮助降低CAM患者的死亡率.
科学领域:
- 传染性疾病 传染性疾病
- 菌类学 菌类学是指菌类学.
- 公共卫生 公共卫生
背景情况:
- 在印度,第二次COVID-19浪潮后,COVID-19相关性粘性菌根症 (CAM) 病例的显著增加.
- 这项研究调查了CAM患者的临床形状,治疗策略和结果.
研究的目的:
- 描述CAM病例的临床特征,管理和结果.
- 确定与CAM患者死亡率相关的因素.
主要方法:
- 从微生物学上确认的CAM病例来自印度十个不同地点 (2021年4月至9月).
- 数据通过结构化问卷和专门的网络门户收集.
- 统计分析包括双变量分析和逻辑回归,使用R版本4.0.2.2.
主要成果:
- 包括336名CAM患者;大多数是男性 (69.1%),识字 (77.7%) 和就业 (66.7%).
- 口腔-面部和眼科症状最常见. 在COVID-19诊断和CAM入院之间的中位数间隔为31天.
- 死亡率为6.9% (23名患者). 较高的HbA1c水平显著增加了死亡的几率 (aOR:1.34).
结论:
- 在COVID-19诊断后推的4-6周的监测期用于早期CAM检测.
- 在入院的CAM患者中强调更好的血糖控制对于降低死亡率至关重要.
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