在COVID-19感染后患者的症状和功能能力之间的关联以及社区控制
Quan Huynh1,2, Noah Wexler1,3, Joel Smith1
1Imaging Research Laboratory, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia.
Internal medicine journal
|July 25, 2023
概括
与对照组相比,COVID-19后患者的功能能力降低,其中27%的患者有主观和14%的客观障碍. 运动训练可以改善选择个体的结果.
科学领域:
- 心脏病学 心脏病学
- 肺部病理学 肺部病理学
- 康复医学 康复医学 康复医学
背景情况:
- COVID-19 (PASC) 或"长期COVID"的后急性后续症状呈现出一般人群中常见的非特异性症状.
- 有限的研究已将PASC症状和功能能力与未感染的对照组进行比较.
研究的目的:
- 为了比较COVID-19幸存者和社区对照者之间的症状和客观功能能力.
- 用标准化测试评估COVID-19对功能障碍的影响.
主要方法:
- 一项以社区为基础的跨部门研究涉及562名COVID-19幸存者和匹配的对照.
- 用杜克活动状态指数 (DASI) 和6分钟步行距离 (6MWD) 评估功能能力.
- 一个子组接受了心肺运动测试,一些人参加了运动前和运动后的训练评估.
主要成果:
- 在562名参与者中,389人 (69%) 在COVID-19后出现症状.
- 在27%的参与者中发现了主观功能障碍 (DASI <85%);14%的参与者有客观功能障碍 (6MWD <85%).
- 与对照组相比,COVID-19幸存者表现出较低的功能能力 (6MWD) 和较高的抑郁率,尽管风险因素较少,年龄较小.
结论:
- 虽然大多数COVID-19幸存者报告了症状,但显著的功能障碍 (主观和客观) 被记录在一个显著的百分比.
- 运动训练显示出潜在的好处,在试点组中,峰值工作量增加了20%.
- 针对性炼计划可能对经历长期COVID相关功能限制的选定患者有益.
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