调整后散射定量超声波的操作者间和操作者内部变异性,用于乳腺质量的表征
Ana K Argueta-Lozano1, Laura Castañeda-Martinez2, Vivian Bass3
1Instituto de Física, Universidad Nacional Autónoma de México, Circuito de la Investigación Científica s/n, Ciudad Universitaria, Mexico City, Mexico.
概括
标准化定量超声波 (QUS) 协议,以估计乳腺病变的回散系数 (BSC),大大降低了操作者间的变化. 这一改进对于可靠地使用QUS对可疑乳腺质量的鉴定至关重要.
科学领域:
- 医疗成像医学成像
- 超声波技术 超声波技术 超声波技术
- 生物医学工程 生物医学工程
背景情况:
- 定量超声波 (QUS) 提供了乳腺损伤特征的潜力.
- 估计回散系数 (BSC) 是一个关键的QUS应用.
- 在BSC估计的变化可能会阻碍临床翻译.
研究的目的:
- 评估一个新的低方差QUS方法的内部和跨操作员变异性,用于乳腺损伤中BSC估计.
- 评估标准化成像协议对BSC变异性的影响.
主要方法:
- 从29个BIRADS 4/5乳腺病变中获得了射频回声信号.
- 使用了两个成像协议,第二个协议涉及重新培训和改进的可复制性措施.
- 使用ANOVA和ICC评估了中位数BSC的内部和跨操作员变异性.
主要成果:
- 最初的协议显示了显著的运营商间变异性 (ICC=0.77).
- 第二个标准化协议显示出优异的运营商间协议 (ICC=0.92),变化不显著.
- 在任何一项协议中,操作者内部的变化都没有显著的意义.
结论:
- 标准化图像采集协议对于降低基于背散射的QUS中运营商间的变异性至关重要.
- 怀疑乳腺质量表征的QUS的成功临床翻译依赖于可重复的方法.
- 新的低方差QUS方法在与标准化协议一起实施时显示出希望.
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