内生性内炎与注射药物使用相关,与其他病因相比
Elizabeth C Ciociola1, Jeffrey C Powell2, Eliza Barnwell3
1Department of Ophthalmology, University of North Carolina School of Medicine, Chapel Hill, North Carolina.
Retina (Philadelphia, Pa.)
|July 25, 2023
概括
注射药物使用者 (IDU) 内的内源性内炎与其他患者呈现的不同. 与注射药物相关的病例通常发生在年轻人中,并发病症较少,积极文化较少.
科学领域:
- 眼科医生 眼科 眼科
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 内源性内眼炎是一种严重的眼内感染.
- 注射药物使用 (IDU) 是众所周知的各种感染的风险因素,包括内.
研究的目的:
- 为了比较内源性内炎的临床特征,在有注射药物使用 (IDU) 病史的患者与其他原因的患者中.
- 确定IDU相关内炎的独特特征,以改善诊断和管理.
主要方法:
- 六年来从三个学术高等保健中心回顾收集数据.
- 介绍特征,微生物学发现,治疗和视力敏度在IDU和非IDU内源性内眼炎组之间的比较.
主要成果:
- 与非IDU患者相比,IDU患者更年轻,更频繁的男性,症状持续时间更长.
- 药物注射组的确诊系统性感染源率 (29%vs71%) 和阳性培养率 (47%vs80%) 显著降低.
- 药物注射患者不太可能住院或接受静脉注射抗菌药物治疗,最终视力敏度没有显著差异.
结论:
- 在IDU患者的内源性内耳炎中,经常出现较少的并发症,缺乏积极的培养或明确的全身源.
- 由于其独特的呈现,高的怀疑指数对于诊断IDU相关的内炎至关重要.
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