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防止阴离子混合使15nm以下短波红外发射稀土基核纳米晶体的量子产量达到50%

Fernando Arteaga Cardona¹, Noopur Jain^2,3, Radian Popescu⁴

¹Institute of Microstructure Technology, Karlsruhe Institute of Technology, Karlsruhe, Germany.

Nature communications

|July 25, 2023

概括

开发明亮的短波红外 (SWIR) 探测器对于生物医学成像至关重要. 这项研究通过控制原子结构,在SWIR纳米晶体中实现了高光发光量子产量,从而实现了体内成像.

科学领域:

生物医学光学生物医学光学
纳米技术纳米技术
材料科学材料科学材料科学

背景情况:

短波红外 (SWIR) 光为光学成像提供了优势,包括减少自身光和组织散射.
目前的SWIR探测器,通常是基于稀土的核心外纳米晶体,由于原子尺度控制不佳,光发光量子产量 (PLQY) 受到限制.
开发更明亮,生物相容的SWIR探头对于推进生物医学应用至关重要.

研究的目的:

研究提高SWIR发射纳米晶体的PLQY的方法.
控制核心外纳米晶体的原子规模组织,以提高光学性能.
为了证明优化SWIR纳米晶体在体内成像中的实用性.

主要方法:

在α-NaYF4:Yb:Er核心上合成的核心外纳米晶体具有同质的 (α-NaYF4) 或异质的 (CaF2) .
通过防止在异质的核心外结构中杂的阳离子,控制了原子规模的组织.
在特定激发功率密度下评估PLQY并进行体内成像.

主要成果:

异质的核心-外结构防止了阴离子混合,显著提高了光学性能.
在60mW/cm2时实现了50%的PLQY,是15nm以下纳米晶体中最高的.
在SWIR区域 (>1450 nm) 成功利用最有效的纳米晶体进行体内成像.

结论:

控制异质核心外纳米晶体中的原子规模组织是提高SWIR探测器效率的关键.
开发的SWIR纳米晶体代表了深层组织光学成像的重大进步.
这项工作为SWIR光成为生物医学成像中的黄金标准铺平了道路.

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