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处方药的使用作为减肥手术后并发症解决措施:基于人口的队列研究
Ted Chia Hao Wu1, Wenjing He1, Isuru Dharmasena2
1Department of Surgery, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB, Canada.
Surgical endoscopy
|July 26, 2023
概括
减肥手术有效地减少了与肥胖相关的疾病,代谢综合征的药物使用减少证明了这一点. 这项以人口为基础的研究跟踪了处方数据,以确认术后的长期并发症解决方案.
科学领域:
- 代谢和腹部手术 代谢和腹部手术
- 药理学 药理学是指药理学的学科.
- 公共卫生 公共卫生
背景情况:
- 肥胖是一种慢性疾病,患病率,死亡率和医疗保健费用都很高.
- 减肥手术是可持续减肥和解决与肥胖相关的并发症最有效的干预措施.
- 测量并发症解决方案往往依赖于自我报告的数据或电子记录,这可能有局限性.
研究的目的:
- 评估减肥手术在解决与肥胖相关的并发症方面的有效性.
- 利用处方药的数据作为共患病的客观衡量标准.
- 为加拿大减肥手术后的长期结果提供基于人口的证据.
主要方法:
- 一项以人口为基础的研究包括1184名在2013年至2019年期间在曼尼托巴省接受胃旁路或袖子胃切除术的患者.
- 从曼尼托巴人口研究数据库获得了手术前和后5年的处方发行数据.
- 此外,还收集了人口统计信息和后续数据.
主要成果:
- 使用降血糖和降脂药物,以及抗高血压药物,在减肥手术后显著减少.
- 在手术后1年,对质子抑制剂和阿片类药物的处方使用暂时增加,然后恢复到基线.
- 对抗抑郁药物,SSRI和甲状腺疾病的药物使用保持稳定.
结论:
- 这项研究是加拿大首次使用省级处方数据库来评估空腹手术后的长期并发症解决方案.
- 与自我报告的数据相比,行政数据提供了一个不那么有偏见的测量结果.
- 结果表明代谢综合征并发症的持续解决,支持减肥手术的长期益处.
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