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CD4 T 细胞和免疫检查点阻塞的毒性

Noah Earland1,2, Wubing Zhang3, Abul Usmani1

  • 1Division of Cancer Biology, Department of Radiation Oncology, Washington University School of Medicine, St. Louis, Missouri, USA.

Immunological reviews
|July 26, 2023
PubMed
概括

在治疗前T细胞和TCR多样性的升高预测了接受免疫检查点抑制剂 (ICI) 的癌症患者的严重免疫相关不良事件 (irAEs). 这一发现有助于预测和预防irrAEs,以获得更安全的免疫疗法.

关键词:
免疫检查点抑制剂 免疫检查点抑制剂与免疫相关的不良事件.免疫疗法 免疫疗法在IRAEs的基础上.黑色素瘤是一种黑色素瘤.预测性的生物标志物

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