lysosome-dependent FOXA1 ubiquitination 有助于晚期前列腺癌的光线系

Sherly I Celada1,2, Guoliang Li1, Lindsay J Celada3

  • 1Department of Biochemistry, Cancer Biology, Neuroscience and Pharmacology, Meharry Medical College, Nashville, TN, USA.

Molecular oncology
|July 26, 2023
PubMed
概括

在前列腺癌 (PCa) 中,SKP2针对FOXA1进行降解. 抑制SKP2通过稳定FOXA1来减少PCa的进展,为晚期疾病提供了一种新的治疗策略.

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