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Updated: Jul 21, 2025

Dissection of Enhancer Function Using Multiplex CRISPR-based Enhancer Interference in Cell Lines
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通过单细胞转录组和表观基因组识别出强大的增强剂基因调节

Fangming Xie1,2, Ethan J Armand3, Zizhen Yao4

  • 1Department of Physics, University of California San Diego, La Jolla, CA 92037, USA.

Cell genomics
|July 26, 2023
PubMed
概括

我们开发了一种新方法,使用单细胞测序将基因增强剂与向基因联系起来. 这种方法控制了基因共同表达,使得增强剂-基因关联研究 (EGAS) 更准确.

关键词:
通过DNA甲基化.脑子 脑子 脑子 大脑染色质可访问性 染色质可访问性增强剂是一种增强剂.显基因组是一个表观基因组.

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