在一个城市周边的三级医院上升性大动脉动脉瘤的频谱:基于心声谱的研究
Ruchika Meel1, Michael Hasenkam2, Ricardo Goncalves3
1Division of Cardiothoracic Surgery, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Frontiers in cardiovascular medicine
|July 26, 2023
概括
胸部上升性大动脉动脉瘤在非洲妇女中很常见,通常与高血压和艾滋病毒有关. 先进的心声回声学可以帮助检测和评估这些动脉瘤的风险.
科学领域:
- 心脏病学 心脏病学
- 血管医学 血管医学
- 医疗成像医学成像
背景情况:
- 胸前上升大动脉动脉瘤 (TAA) 是死亡率和发病率的重要原因.
- 关于非洲TAA动脉瘤的数据有限.
- 这项研究研究了TAA动脉瘤在城市周边的三级医院环境中的特征.
研究的目的:
- 在特定的非洲人群中描述TAA动脉瘤的谱.
- 为了确定TAA动脉瘤的常见病因和临床表现.
- 评估心声回声和应变成像在TAA动脉瘤评估中的实用性.
主要方法:
- 从2017年10月到2022年10月,对139例TAA动脉瘤病例和45例对照进行了回顾性研究.
- 利用临床和心声学数据,包括用于左心室和大动脉应变分析的先进应变成像.
- 测量了大动脉尺寸,左心室喷射率和大动脉周围应变 (CS).
主要成果:
- 该研究包括139例TAA动脉瘤病例 (52.5%为女性,95%为非洲人),主要病因是高血压和艾滋病毒.
- 患者经常出现心力衰竭 (69.7%) 和大动脉反 (50.3%严重).
- 与对照组相比,在TAA动脉瘤患者中观察到左心室喷射率的减少,大动脉CS和大动脉硬度的增加.
结论:
- 在这个非洲人口中,TAA动脉瘤经常与高血压和艾滋病毒有关,导致显著的发病率和死亡率.
- 二维回声心电图和先进的应变成像显示,有望检测和风险分层TAA动脉瘤.
- 早期检测和管理对于改善TAA动脉瘤患者的治疗结果至关重要.
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