使用下一代知识发现方法,探索抗癌药物的潜在分子机制和基因毒性

Peter Natesan Pushparaj1, Mahmood Rasool2, Muhammad Imran Naseer3

  • 1Peter Natesan Pushparaj, PhD Associate Professor Center of Excellence in Genomic Medicine Research, Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences King Abdulaziz University, Jeddah, Saudi Arabia.

概括

这项研究使用了学方法来评估抗癌药物毒性和分子机制,识别了像TP53信号传递等参与细胞死亡和基因毒性相关的途径,以获得更安全的药物开发.

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