HbA1c与血清铁和转移素和的相关性 在非糖尿病铁缺乏症患者中
Darshan Kumar1, Tazeen Rasheed2, Bader Faiyaz Zuberi3
1Darshan Kumar (FCPS) Professor, Department of Medicine DIKIOHS, Dr. Ishrat-ul-Abad Institute of Oral Health Sciences, Dow University Health Sciences Karachi.
Pakistan journal of medical sciences
|July 26, 2023
概括
在非糖尿病患者中,较低的铁含量和转林和与较高的HbA1c相关. 纠正铁缺乏症对于患者准确的HbA1c解释至关重要.
科学领域:
- 临床生物化学 临床生物化学
- 血液学 血液学 血液学
背景情况:
- 糖化血红蛋白 (HbA1c) 是血糖控制的一个关键标志物.
- 缺铁是一种常见的疾病,可能会影响各种生化标志物.
研究的目的:
- 为了研究HbA1c水平和铁状况 (血清铁和转激素和) 之间的相关性,在非糖尿病铁缺乏症患者中.
主要方法:
- 一项横截面研究将非糖尿病患者患有缺铁性贫血 (ID) 与健康对照进行了比较.
- 测量了HbA1c,CBC,血清铁和总铁结合能力.
- 计算了转激素和度 (TSAT),并使用肯德尔tau-b测试分析了相关性.
主要成果:
- 与对照组 (5.52±0.50) 相比,缺铁组 (5.89±0.43) 的平均HbA1c显著更高 (p<.001).
- HbA1c水平与血红蛋白,血清铁和转激素和有显著的负相关性 (p<.001).
结论:
- 较低的血清铁和转林和与非糖尿病人的HbA1c水平升高有关.
- 在解释HbA1c结果之前,应该考虑和纠正铁的状态,以确保准确性.
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