与呼吸系统病毒相关的成年人脑膜炎
Seon-Jae Ahn1,2, Jangsup Moon2,3, Jun-Sang Sunwoo1,4
1Center for Hospital Medicine, Seoul National University Hospital, Seoul, Korea.
Encephalitis (Seoul, Korea)
|July 26, 2023
概括
呼吸道病毒脑膜炎可以影响成年人. 建议进行多重PCR查,以诊断RV中枢神经系统感染,即使没有呼吸道症状.
科学领域:
- 神经学 神经学
- 传染性疾病 传染性疾病
- 病毒学 病毒学
背景情况:
- 众所周知,呼吸道病毒 (RV) 导致中枢神经系统 (CNS) 感染,主要记录在儿科患者中.
- 最近的报道表明,成年人出现VR相关脑膜炎的新兴趋势.
- 关于VR中枢神经系统感染在成人神经感染注册表中的患病率和特征的研究有限.
研究的目的:
- 在一个神经感染注册表中调查与VR相关的脑膜炎在成年患者中的发生率和临床特征.
- 确定RV多重聚合酶链反应 (PCR) 在成年脑膜炎病例中的诊断效用.
主要方法:
- 首尔国立大学神经感染登记册的回顾性审查.
- 通过VR多重PCR查诊断出VR脑膜炎的10名成年患者的鉴定.
- 对这些患者的临床表现,实验室发现和临床结果的分析.
主要成果:
- 三例确诊为确定的RV脑膜炎,脑脊液中PCR呈阳性.
- 七个病例被归类为可能的RV脑膜炎,在唾液中呈阳性PCR,在广泛的检查中呈阴性结果.
- 这项研究确定了RV脑膜炎是成年人神经疾病的潜在原因.
结论:
- 在成人脑膜炎的差异诊断中应考虑RV脑膜炎.
- RV PCR查是一种有价值的诊断工具,即使没有典型的上呼吸道感染症状,也建议使用.
- 早期诊断和考虑RV对于管理成人脑膜炎至关重要.
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