评估实施科学的转化到临床人工智能的转化:对定性研究的文献计量研究
H D J Hogg1,2,3, M Al-Zubaidy2, P A Keane3,4
1Faculty of Medical Sciences, Newcastle University, Newcastle Upon Tyne, United Kingdom.
Frontiers in health services
|July 26, 2023
概括
理论,模型或框架 (TMF) 很少在定性临床AI研究中使用. 改进TMF应用可以弥合"人工智能沟",并提高临床AI在实践中的实施.
科学领域:
- 实施科学 实施科学
- 人工智能的人工智能
- 医疗信息学 医疗信息学
背景情况:
- 临床人工智能 (AI) 是有前途的,但面临着重大的实施差距.
- 理论,模型或框架 (TMF) 在实施研究中的应用在理论上是有利的,但缺乏对其影响的清晰度.
- 在定性临床人工智能研究中了解TMF的使用对于改善研究实践和人工智能采用至关重要.
研究的目的:
- 在定性临床人工智能研究中测量和描述TMF的应用.
- 确定增强研究实践和改善临床AI实施的机会.
- 评估这一领域的TMF的频率,选择,理由和应用.
主要方法:
- 对临床AI (2014-2022) 利益相关者的观点进行定性研究的系统识别.
- 根据出版物类型,临床/地理背景,AI类型,数据收集,参与者和TMF应用,对符合条件的研究进行表征.
- 详细分析每一个应用的TMF,其理由和应用方式.
主要成果:
- 在202项符合条件的研究中,只有34.7%的研究采用了TMF,但随着时间的推移,TMF的采用没有显著增加.
- 使用了各种各样的TMF,大多数只应用一次;技术接受模型是最常见的.
- TMF的应用往往没有充分的理由,对替代框架或限制的讨论有限;数据分析是最常见的应用方法.
结论:
- 在定性临床人工智能研究中,TMF的利用不足,对选择的共识有限,应用理由不明确.
- 提高TMF应用的严谨性和频率是改善实施科学对临床AI的影响的关键机会.
- 建议增加可访问性和与理论知情实践的接触,以弥合这一差距.
- 人工智能沟的深
- 并促进人工智能转化为现实世界护理.
更多相关视频
05:47Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
296
03:14Augmenting Large Language Models via Vector Embeddings to Improve Domain-Specific Responsiveness
Published on: December 6, 2024
624
相关概念视频
Improving Translational Accuracy
2.6K
2.6K
Translation
142.4K
Lesson: Translation
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of...
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of...
142.4K
Issues And Trends In Healthcare Delivery System
5.7K
The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
5.7K
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
148
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
148
Initiation of Translation
34.2K
Initiating translation is complex because it involves multiple molecules. Initiator tRNA, ribosomal subunits, and eukaryotic initiation factors (eIFs) are all required to assemble on the initiation codon of mRNA. This process consists of several steps that are mediated by different eIFs.
First, the initiator tRNA must be selected from the pool of elongator tRNAs by eukaryotic initiation factor 2 (eIF2). The initiator tRNA (Met-tRNAi) has conserved sequence elements including modified bases at...
First, the initiator tRNA must be selected from the pool of elongator tRNAs by eukaryotic initiation factor 2 (eIF2). The initiator tRNA (Met-tRNAi) has conserved sequence elements including modified bases at...
34.2K
Leaky Scanning
5.2K
During most eukaryotic translation processes, the small 40S ribosome subunit scans an mRNA from its 5' end until it encounters the first start AUG codon. The large 60S ribosomal subunit then joins the smaller one to initiate protein synthesis. The location of the translation initiation is largely determined by the nucleotides near the start codon as there may be multiple translation initiation sites present on the mRNA. Marilyn Kozak discovered that the sequence RCCAUGG (where R...
5.2K
