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在韩国,吸烟状态与COVID-19死亡之间的关联:一项全国性的队列研究
1Community Care Research Center, Health Insurance Research Institute, National Health Insurance Service, Wonju, Republic of Korea.
Tobacco induced diseases
|July 26, 2023
概括
目前的吸烟者和最近戒烟者面临着明显更高的COVID-19死亡风险. 持续戒烟对于降低COVID-19患者死亡率至关重要.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 呼吸系统医学 呼吸系统医学
背景情况:
- 随着COVID-19的流行,各种风险因素对疾病的严重程度和死亡率的影响得到了突出强调.
- 吸烟是众多呼吸道和心血管疾病的已知危险因素,但它对COVID-19死亡率的具体影响需要进一步调查.
研究的目的:
- 调查COVID-19诊断的个人中吸烟状态和死亡风险之间的关联.
- 为了确定不同的吸烟状态 (目前吸烟者,最近戒烟者,长期戒烟者,从未吸烟者) 是否会导致COVID-19死亡率的不同风险.
主要方法:
- 利用来自韩国国家健康保险服务的全国性队列数据.
- 包括2020年1月1日至5月30日期间检测出严重急性呼吸系统综合征冠状病毒2 (SARS-CoV-2) 阳性的人.
- 根据2015年至2018年期间进行的国家健康查评估吸烟状况,并根据混因素进行调整.
主要成果:
- 分析包括4259名阳性SARS-CoV-2患者.
- 与从未吸烟者相比,目前吸烟者和最近戒烟者患COVID-19的死亡风险显著增加 (AOR从3.74到3.75不等).
- 与目前的吸烟者相比,长期戒烟者和从未吸烟的人的COVID-19死亡风险较低 (AOR分别为0.33和0.27).
结论:
- 吸烟状态与COVID-19患者死亡风险增加有显著的关联.
- 强烈建议当前吸烟者和最近戒烟者继续戒烟,以减轻死亡风险.
- 长期戒烟似乎可以降低COVID-19相关死亡的风险.
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