评估与年龄相关的眼睛支系统的变化
Ahmed Makarem1, Ahmed Abass1,2, Fangjun Bao3
1School of Engineering, University of Liverpool, Liverpool, United Kingdom.
Frontiers in bioengineering and biotechnology
|July 26, 2023
概括
这项研究通过反向分析估计了轨道软组织的度. 硬度随年龄显著变化,特别是在年轻人与老年人之间,并且比以前认为的更硬.
科学领域:
- 眼科医生 眼科 眼科
- 生物力学 生物力学
- 医疗成像医学成像
背景情况:
- 精确估计轨道软组织 (OST) 生物机械性质对于理解眼动力学至关重要.
- 之前的研究缺乏与年龄和眼睛反应相关的OST度的详细分析.
研究的目的:
- 通过反向数值分析方法估计人类轨道软组织 (OST) 的材料刚度.
- 为未来关于动态度计和眼科条件模拟的研究提供数据.
主要方法:
- 从使用Corvis ST和Pentacam的185名中国参与者收集了临床数据.
- 开发了185个数值眼睛模型,使用角膜断层扫描和理想化的OST几何.
- 利用在气泡负荷下眼睛运动的反向分析来确定OST刚度参数.
主要成果:
- 轨道软组织硬度与年龄的相关性较弱,但年龄组之间存在显著差异 (20-43岁,相比43-63岁和63-91岁).
- 发现OST比之前报告的脂肪组织硬近四倍.
- 在气泡加载时眼球旋转可能涉及眼睛后部部件.
结论:
- 轨道软组织的度与年龄有关,在老年人中观察到显著的变化.
- 据估计,OST的硬度远远高于之前的假设.
- 需要进一步研究后部球体在眼睛对动力力量的反应中的作用.
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