瑞COVID-19疫苗的常见副作用:来自巴基斯坦的经验
Syed Muhammad Safi Haider1, Shaf Ali Alvi1, Hamza Khan2
1Internal Medicine, Hamdard College of Medicine and Dentistry, Karachi, PAK.
Cureus
|July 26, 2023
概括
瑞-生物科技公司的疫苗.
科学领域:
- 免疫学 免疫学 免疫学
- 疫苗学 疫苗学 疫苗学
- 公共卫生 公共卫生
背景情况:
- 严重急性呼吸道综合征冠状病毒2 (SARS-CoV-2) 的快速传播需要广泛接种疫苗.
- 基于mRNA的COVID-19疫苗Pfizer-BioNTech疫苗是第一个广泛分发的疫苗之一.
- 了解不良反应的患病率和性质对于疫苗接受和公共卫生战略至关重要.
研究的目的:
- 为了评估 Pfizer-BioNTech COVID-19 疫苗后副作用的发生率.
- 确定第一剂和第二剂后常见的局部和全身不良反应.
- 为了比较第一剂和第二剂疫苗之间副作用的发生率.
主要方法:
- 一项涉及1000名接受了两剂Pfizer-BioNTech疫苗的参与者的多中心,横截面研究.
- 收集的数据包括人口统计,并发症,疫苗接种史和报告的副作用.
- 在六个月的时间内,在接种了第一剂和第二剂疫苗后,记录了副作用.
主要成果:
- 瑞疫苗第一剂后最常见的副作用是注射部位灼热 (70.4%) 和发烧 (70.0%).
- 在第二剂后,肌肉疼痛是62.8%的参与者报告的最常见的副作用.
- 总的来说,第一剂疫苗与第二剂相比,副作用的发生率更高.
结论:
- 瑞-生物科技疫苗与几种不良反应有关,包括注射部位反应和系统性症状,如发烧和肌肉疼痛.
- 疫苗的第一剂似乎比第二剂更频繁地引起副作用.
- 对疫苗副作用的监测和报告对于持续的疫苗安全监测至关重要.
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