对头部和部状细胞癌的治疗后跟踪指南的遵守价值
Ashley Stone1, Jianyou Liu2, Juan Lin2
1Albert Einstein College of Medicine, Bronx, New York, USA.
The Laryngoscope
|July 26, 2023
概括
在治疗后的第一年遵守头癌随访指南可以改善存活率. 五年来持续的坚持并没有显示出显著的生存益处.
科学领域:
- 在瘤学瘤学.
- 癌症研究 癌症研究
- 临床医学 临床医学
背景情况:
- 对头角状细胞癌 (HNSCC) 进行密集的治疗后监测的临床实用性仍然是争论的主题.
- 有效的后续策略对于改善HNSCC患者的治疗结果至关重要.
研究的目的:
- 评估国家综合癌症网络 (NCCN) 对HNSCC的治疗后随访指南的遵守情况.
- 确定遵守指南和患者生存结果之间的关联.
主要方法:
- 分析了来自城市学术医疗中心的452名HNSCC患者的队列.
- 患者根据遵守NCCN后续指南进行了分层.
- 进行了生存分析,以评估遵守对整体和特定疾病生存时间的影响.
主要成果:
- 只有23.5%的患者在治疗后的第一年遵守了NCCN的指导方针,15.9%的患者在五年内遵守了指导方针.
- 一年守与改善的5年整体存活率 (HR 0.634) 和疾病特异性存活率 (HR 0.556) 显著相关.
- 五年来持续的坚持并没有显示出与生存结果的显著关联. 复发分析显示,坚持和早期复发之间没有关联.
结论:
- 在HNSCC治疗后的第一年内遵守NCCN随访指南与更好的5年生存率有关.
- 在整个五年期间,没有观察到对生存的益处与一致的坚持.
- 这些发现强调了在HNSCC管理中早期治疗后随访的重要性.
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