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Updated: Jul 21, 2025

Monitoring GPCR-β-arrestin1/2 Interactions in Real Time Living Systems to Accelerate Drug Discovery
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C5a,C5aR2和β-arrestin1的三元模型结构复合体

Pulkit Kr Gupta1, Aurosikha Das1, Aditi Singh1

  • 1Chemical Biology Laboratory, School of Basic Sciences, Indian Institute of Technology Bhubaneswar, Bhubaneswar, Odisha, India.

Journal of biomolecular structure & dynamics
|July 26, 2023
PubMed
概括

这项研究模拟了补充片段5a (C5a) 的活性三元复合体及其受体C5aR2和β-arrestin1. 这为了解通过β-arrestins传递C5aR2信号的结构基础,这对于炎症反应至关重要.

关键词:
这是一个C5a受体.补充系统的补充系统.分子动力学分子动力学主要组件分析的主要组件分析三元复合体是一个三元复合体.

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