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Updated: Jul 21, 2025

Deciphering Molecular Mechanism of Histone Assembly by DNA Curtain Technique
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Deciphering Molecular Mechanism of Histone Assembly by DNA Curtain Technique

Published on: March 9, 2022

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基因组伴侣和重塑剂的核细胞保留阻断了普遍的DNA-蛋白质结合

Felix Jonas1, Matan Vidavski1, Eli Benuck1

  • 1Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.

Nucleic acids research
|July 26, 2023
PubMed
概括

这项研究揭示了关键蛋白质 (基因组伴侣和重塑者) 在基因活动期间如何维持DNA包装. 削减这些调节剂显示了它们在保护基因体内核体稳定性的特定作用,这对基因组完整性至关重要.

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In Vitro Characterization of Histone Chaperones using Analytical, Pull-Down and Chaperoning Assays08:16

In Vitro Characterization of Histone Chaperones using Analytical, Pull-Down and Chaperoning Assays

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