转移性扩散的卵泡变异乳头甲状腺癌没有宫淋巴结转移,呈现与hypopituitarism相关的症状
Muhammed Kızılgül1, Ömer Bayır2, Bekir Uçan1
1Department of Endocrinology and Metabolism, University of Health Sciences, Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey.
Einstein (Sao Paulo, Brazil)
|July 26, 2023
概括
这项案例研究突出了一个罕见的乳头甲状腺癌扩散到垂体腺体的罕见情况,导致激素缺乏. 早期诊断和多学科护理对于管理这种罕见的转移性疾病至关重要.
科学领域:
- 内分泌学 在内分泌学.
- 在瘤学瘤学.
- 神经外科 神经外科
背景情况:
- 乳头甲状腺癌 (PTC) 是最常见的甲状腺恶性瘤.
- 毛囊变异PTC是一种不常见的亚型.
- 下垂体转移是各种癌症的罕见并发症.
研究的目的:
- 报告一种罕见的扩散卵泡变异乳头甲状腺癌与垂体转移的罕见病例.
- 强调在患有下垂体和垂体病变的患者中考虑垂体转移的重要性.
- 讨论这种罕见疾病的诊断和治疗策略.
主要方法:
- 一个74岁的男性患上上腺和甲状腺功能不全的症状的病例介绍.
- 诊断工作包括成像 (垂体MRI,甲状腺超声波),细针吸收,以及组织病理/免疫组织化学评估.
- 治疗包括全甲状腺切除术,跨形手术,放射性治疗,玛刀放射治疗和索拉费尼布治疗.
主要成果:
- 这名患者被诊断出患有扩散的卵泡变异 papillary 甲状腺癌和垂体转移.
- 为视野缺陷和垂体质量进行了手术干预.
- 多模式治疗包括放射性,放射治疗和向治疗 (sorafenib) 导致甲状腺球蛋白水平降低.
结论:
- 应考虑在患有低垂体和垂体质量患者中进行垂体转移.
- 视野缺陷可能表明需要进行神经外科干预.
- 多学科管理对于优化罕见转移性甲状腺癌病例的预后至关重要.
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