非经典的叶状癌在瘤切除边缘增加局部复发吗?
Anna C Beck1, Solange Bayard2, George Plitas1
1Breast Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Annals of surgical oncology
|July 26, 2023
概括
非古典性乳球癌 in situ (NC-LCIS) 的边缘宽度不会影响侵袭性乳腺癌隆瘤切除术后的异侧乳腺瘤复发 (IBTR) 或局部区域复发 (LRR). 重新切割的决定应该集中在侵袭性癌症边缘上,而不是NC-LCIS.
科学领域:
- 在瘤学瘤学.
- 手术病理学手术病理学
- 乳腺癌研究研究 乳腺癌研究
背景情况:
- 在侵袭性癌症切除后手术边缘的非经典的局部叶状癌 (NC-LCIS) 的临床意义尚未得到充分确立.
- 这项研究调查了NC-LCIS边际状态与乳腺癌患者复发风险之间的关联.
研究的目的:
- 确定在侵袭性乳腺癌边缘或附近的NC-LCIS是否会影响ipsilateral乳腺瘤复发 (IBTR) 和局部区域复发 (LRR).
主要方法:
- 对511名患有0-III期乳腺癌和NC-LCIS的女性患者进行了回顾性分析,这些患者接受了淋巴切除术 (2010-2022年).
- NC-LCIS边缘被分为<2毫米,≥2毫米,或在剃须边缘内.
- IBTR和LRR的比率是根据保证金状态进行评估的.
主要成果:
- 不同的NC-LCIS边际状态之间没有观察到IBTR或LRR率的显著差异 (IBTR为p=0.8,LRR为p=0.9).
- 原始IBTR发生率为3.3%,LRR发生率为4.9%.
- 具体率:IBTR (3.7%≥2毫米,0%<2毫米,3.2%的剃须);LRR (4.9%≥2毫米,2.7%<2毫米,5.6%的剃须).
结论:
- 在完全切除的侵入性乳腺癌中,NC-LCIS的边际宽度与IBTR或LRR风险无关.
- 对于重新切割的外科决定,应优先考虑侵袭性癌症的边缘,而不是NC-LCIS边缘.
关键词:
乳腺癌 乳腺癌 乳腺癌在位管道癌的管道癌.在位的叶状癌 (lobular carcinoma)当地复发局部复发瘤切除术 (Lumpectomy) 是一种切除术.边际的宽度边际的宽度重复切割的方法是更多相关视频
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