甲状腺眼病手术治疗后眼部生物机械反应参数和眼内压力的变化
Yun Hsia1,2, Yi-Hsuan Wei2,3, Shu-Lang Liao2,3
1Department of Ophthalmology, National Taiwan University Hospital Hsin-Chu Branch, Hsinchu, Taiwan.
Investigative ophthalmology & visual science
|July 26, 2023
概括
甲状腺眼病 (TED) 手术可以改变眼部生物力学和眼内压力 (IOP) 测量. 轨道减压显著降低了IOP-NCT,而前侧白血切除术并没有显著改变IOP.
科学领域:
- 眼科医生 眼科 眼科
- 眼部生物力学 眼部生物力学
- 甲状腺眼睛疾病 甲状腺眼睛疾病
背景情况:
- 甲状腺眼部疾病 (TED) 是一种影响视轨道的自身免疫性疾病.
- 手术干预,如轨道减压和前白切除术,用于管理TED.
- 手术后眼部生物力学特性和眼内压力 (IOP) 的变化需要进行调查.
研究的目的:
- 在TED患者中评估眼睛生物机械反应参数和IOP在轨道减压或前白切除后的变化.
- 评估这些外科手术对IOP测量的影响.
主要方法:
- 追溯分析了46名接受轨道减压的患者的83只眼睛和28名接受前白切除的患者的45只眼睛.
- 科维斯ST度仪用于眼部生物力学和生物力学纠正的IOP (bIOP) 的术前和术后评估.
- 无接触度计 (IOP-NCT) 也进行.
主要成果:
- 前方白切除术:边缘反射距离减小;最大腔半径和整个眼睛运动增加;IOP-NCT或bIOP没有显著变化.
- 轨道减压:眼外膜和A2长度下降;bIOP没有显著变化,但IOP-NCT显著下降.
- 较高的基线IOP-NCT和更大的降低度参数A1与更大的IOP-NCT降低轨道解压后相关.
结论:
- 在TED手术后,眼睛的生物力学参数可能会发生变化,影响IOP测量.
- 轨道减压显著影响IOP-NCT,这表明改变的眼部生物力学会影响度计读数.
- 在解释TED患者手术后的IOP时,需要仔细考虑生物力学变化.
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