在妊娠糖尿病中评估胎儿心肌性能指数

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Merve Ozturk¹, Zahid Agaoglu¹, Filiz Halici Ozturk¹

¹Department of Perinatology, Turkish Ministry of Health, Ankara City Hospital, Ankara, Turkey.

Congenital anomalies

|July 26, 2023

概括

胎儿心肌性能指数 (MPI) 在妊娠期糖尿病 (GDM) 的怀孕中更高. 胎儿MPI升高可能表明潜在的不良结果,有助于检测GDM母亲胎儿的风险.

科学领域:

心脏病学心脏病学
孕产妇和胎儿医学孕产妇和胎儿医学
新生儿科学新生儿科学

背景情况:

孕期糖尿病 (GDM) 对胎儿健康构成风险.
评估胎儿心脏功能对于管理GDM怀孕至关重要.
心肌性能指数 (MPI) 是心脏功能的敏感指标.

研究的目的:

为了比较胎儿心肌性能指数 (MPI) 在GDM怀孕与健康对照.
调查胎儿MPI与母亲葡萄糖水平之间的关系.
为了评估胎儿MPI对不良周产期结果的预测值.

主要方法:

对90名孕妇 (50名孕妇,40名对照) 的前性研究.
使用同体积度收缩时间 (ICT),同体积度放松时间 (IRT) 和喷射时间 (ET) 计算胎儿的MPI.
胎儿MPI,PR间隔,E/A比率,母体葡萄糖水平和新生儿结局的比较.

主要成果:

胎儿MPI在GDM组 (0.43 ± 0.04) 与对照组 (0.40 ± 0.06) 相比显著更高.
一个MPI切线>0.41预测了70%的灵敏度和68%的特异性不良周产期结果.
在胎儿的MPI和母亲的禁食,食后葡萄糖或HbA1c水平之间没有发现相关性.

结论:

胎儿MPI在怀孕中受损GDM.
在GDM中较高的MPI值,特别是需要胰岛素的MPI值,与新生儿不良后果有关.
胎儿MPI作为一种有价值的工具,用于识别由于心脏功能受损而面临不良结果风险的胎儿.

关键词:

糖尿病糖尿病患者糖尿病患者胎儿的心脏胎儿的心脏心肌功能指数表现指数怀孕怀孕怀孕怀孕怀孕

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