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Updated: Jul 21, 2025

Monitoring eIF4F Assembly by Measuring eIF4E-eIF4G Interaction in Live Cells
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mTOR抑制通过调节eIF3D介导的选择性mRNA翻译来重新编程细胞蛋白质稳定,并促进细胞表型切换

Sejeong Shin1, Min-Joon Han2, Mark P Jedrychowski3

  • 1Department of Physiology and Biophysics, University of Illinois College of Medicine at Chicago, Chicago, IL 60612, USA.

Cell reports
|July 26, 2023
PubMed
概括

拉巴胺素 (mTOR) 抑制的机械标激活翻译因子eIF3D,促进细胞表型切换. 这突显了细胞如何动态地改变蛋白质稳定和细胞命运.

关键词:
CP: 细胞生物学 细胞生物学科普:分子生物学 分子生物学在eIF3D中,您可以使用eIF3D.在 eIF4E 中,您可以使用 eIF4E.在mRNA的翻译过程中,mRNA的翻译在mTOROR中使用mTOR.蛋白质组是蛋白质组的组成部分.蛋白质稳定症是一种蛋白质稳定症.

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