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美国新生儿重症监护病房中的当前益生菌使用模式:一个多机构调查
Morcos Hanna1, Irfan Ahmad2, Toby Yanowitz3
1Division of Neonatology, Department of Pediatrics, Baylor College of Medicine, Houston, Texas.
American journal of perinatology
|July 26, 2023
概括
在美国NICU中,早产婴儿的益生菌使用正在增加,但实践在很大程度上有所不同. 美国儿科学会 (AAP) 的声明产生了适度的影响,强调了对标准化指导方针和监管的需要.
科学领域:
- 新生儿护理 新生儿护理
- 儿科胃肠病学 儿科胃肠病学
- 微生物组研究的研究.
背景情况:
- 益生菌补充剂被认为对早产婴儿的潜在健康益处.
- 2021年美国儿科学会 (AAP) 声明建议谨慎使用益生菌,因为实践异质性和缺乏联邦监管.
研究的目的:
- 评估2021年AAP声明对新生儿重症监护室 (NICU) 益生菌使用的影响.
- 评估目前在美国NICU中补充益生菌的机构模式.
主要方法:
- 在儿童医院新生儿联盟 (CHNC) 和儿科医学集团 (Pediatrix Medical Group) 内的430个机构中分发了一项横截面的基于网络的调查.
- 该调查收集了有关益生菌配方,启动/终止标准,中止原因以及AAP声明的影响的数据.
主要成果:
- 39%的响应医院 (共95家) 目前使用益生菌,报告有14种不同的配方.
- 在24%的医院中,AAP声明影响了决策,导致11%停止使用;37%的非用户正在考虑启动.
- 在益生菌配方,启动标准 (例如,出生体重<1,500克,妊娠年龄<32周) 和父母同意实践 (30%的机构) 中存在显著的变化.
结论:
- 美国NICU中益生菌的使用正在增加,但其特点是显著的变化.
- 2021年AAP声明对当前的临床实践产生了变化和适度的影响.
- 需要加强联邦监管和达成共识的指导方针,以标准化在早产婴儿中使用益生菌.
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